{"id":160209,"date":"2025-12-16T17:22:40","date_gmt":"2025-12-16T17:22:40","guid":{"rendered":"https:\/\/www.kidneyresearchuk.org\/?p=160209"},"modified":"2025-12-16T17:22:57","modified_gmt":"2025-12-16T17:22:57","slug":"could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health","status":"publish","type":"post","link":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/","title":{"rendered":"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health?"},"content":{"rendered":"\r\n

In a study\u00a0<\/a>published in\u00a0Cardiovascular Research, Dr Jess\u00a0Ivy\u00a0and the team at the University of Edinburgh, with funding from Kidney Research UK, have shown\u00a0that\u00a0studying\u00a0changes in\u00a0small blood vessels in the kidney\u00a0in models\u00a0during sleep\u00a0could improve our understanding of\u00a0heart and vessel health\u00a0in\u00a0kidney\u00a0disease\u00a0patients.\u00a0\u00a0<\/p>\r\n

\"Three

How does blood pressure change\u00a0during sleep?<\/h2>\r\n

Usually,\u00a0blood pressure<\/a>\u00a0is\u00a0lower\u00a0when asleep\u00a0than when awake. This is part of the\u00a0body’s\u00a0natural rhythm.\u00a0However,\u00a0people with chronic kidney disease<\/a> (CKD)\u00a0are more likely to\u00a0have\u00a0blood pressure that\u00a0doesn’t\u00a0decrease\u00a0during sleep,\u00a0which is\u00a0called non-dipping blood pressure.\u00a0Non-dipping blood pressure\u00a0is\u00a0thought to be worse\u00a0for heart and blood vessel health,\u00a0and increases\u00a0the risk of\u00a0a cardiovascular<\/a> event, such as a heart attack or stroke.\u00a0\u00a0<\/p>\r\n

How\u00a0could\u00a0steroid hormones change blood pressure\u00a0during sleep?<\/h2>\r\n

The body\u00a0produces\u00a0many naturally occurring hormones, this includes\u00a0steroid hormones.\u00a0Glucocorticoids are a steroid hormone\u00a0essential for normal bodily functions and\u00a0their\u00a0levels\u00a0vary throughout the day.\u00a0\u00a0<\/p>\r\n

In laboratory models, altering the natural levels of glucocorticoids can trigger non-dipping blood pressure. Steroids, which are artificial versions of the body’s natural glucocorticoids, are widely used medicines to help reduce inflammation (part of the body’s defence system) in conditions where it is damaging the body’s own tissues. People living with long term conditions, such as diabetes<\/a>, can also have changes to the body’s natural levels of glucocorticoids. \u00a0<\/p>\r\n

A closer look at glucocorticoids and kidney vessels\u00a0<\/h2>\r\n

Jess and the team have been\u00a0studying\u00a0the effect of glucocorticoids on the\u00a0small tubes\u00a0which carry\u00a0blood\u00a0into the kidney, called the renal arteries.\u00a0Widening and narrowing of the renal arteries\u00a0controls\u00a0the blood flow into the kidney,\u00a0which is\u00a0an important mechanism for\u00a0helping the kidneys\u00a0to\u00a0control blood pressure.\u00a0\u00a0\u00a0<\/p>\r\n

To test the effect of glucocorticoids on the renal arteries, Jess and the team gave a laboratory model continuous glucocorticoids, to reduce its natural rhythm. They found that in this model the renal arteries lost their normal pattern of widening and narrowing while awake or asleep. They also found that different genes, which are small sections of DNA, were switched on and off in different rhythms. These changes to the widening and narrowing of the renal arteries, and the genes switched on and off, showed model renal arteries respond to rhythmic glucocorticoid levels, which could then influence blood pressure control by the kidney.\u00a0<\/p>\r\n

What could this mean for kidney patients?\u202f\u00a0<\/h2>\r\n

By looking at the\u00a0effect\u00a0of glucocorticoid levels on\u00a0the\u00a0kidneys, we\u00a0could increase understanding of\u00a0the mechanisms\u00a0behind\u00a0blood pressure\u00a0changes\u00a0during sleep.\u00a0This could lead to new\u00a0ways of\u00a0protecting the vessel health of\u00a0kidney patients\u00a0in the future\u00a0and form\u00a0a new approach\u00a0to improving\u00a0cardiovascular health.\u00a0\u00a0<\/p>\r\n

David Crosby,<\/b> chief research officer at Kidney Research UK commented:<\/strong>\u00a0“We need to find new ways of protecting cardiovascular health in kidney patients who are at an increased risk of having an event such as a heart attack, heart\u00a0failure\u00a0or stroke.\u00a0This\u00a0new approach\u00a0to better understand how blood pressure changes during sleep could\u00a0potentially\u00a0inform new ways of protecting cardiovascular health in kidney patients.\u00a0More research is needed\u00a0to develop this concept, and we look forward to the next steps.”\u00a0<\/p>\r\n

*\u00a0This is an experimental study and no changes to medications should be made without advice from a healthcare professional.\u00a0<\/p>\r\n

\"Kidney

Have you been diagnosed with kidney disease?<\/h2>\r\n

Request your free Kidney Kit today.<\/p>\r\n

You’ll find tips and support from kidney patients, delicious recipes, simple exercise plans and more.<\/p>\r\n

Get your free Kidney Kit <\/a><\/p>\r\n

Why not make a donation now?<\/h2>\r\n

Every \u00a3 counts towards transforming treatments for people living with kidney disease.<\/p>\r\n

Donate now <\/a><\/p>\r\n","protected":false},"excerpt":{"rendered":"

In a study\u00a0published in\u00a0Cardiovascular Research, Dr Jess\u00a0Ivy\u00a0and the team at the University of Edinburgh, with funding from Kidney Research UK, have shown\u00a0that\u00a0studying\u00a0changes in\u00a0small blood vessels in the kidney\u00a0in models\u00a0during sleep\u00a0could improve our understanding of\u00a0heart and vessel health\u00a0in\u00a0kidney\u00a0disease\u00a0patients.\u00a0\u00a0 Jess Ivy, Georgios Krilis and Anastasiia Komolova in the lab How does blood pressure change\u00a0during sleep? Usually,\u00a0blood pressure\u00a0is\u00a0lower\u00a0when…<\/p>\n","protected":false},"author":3,"featured_media":160210,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_searchwp_excluded":"","footnotes":""},"categories":[344,29],"tags":[],"class_list":["post-160209","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blood-pressure","category-research"],"acf":[],"yoast_head":"\nCould understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health? - Kidney Research UK<\/title>\n<meta name=\"description\" content=\"Dr Jess Ivy has shown that studying changes in blood vessels in the kidney could improve our understanding of heart and vessel health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health? - Kidney Research UK\" \/>\n<meta property=\"og:description\" content=\"Dr Jess Ivy has shown that studying changes in blood vessels in the kidney could improve our understanding of heart and vessel health.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\" \/>\n<meta property=\"og:site_name\" content=\"Kidney Research UK\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kidneyresearchuk\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-16T17:22:40+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-16T17:22:57+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1442\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Amy\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Kidney_Research\" \/>\n<meta name=\"twitter:site\" content=\"@Kidney_Research\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Amy\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\"},\"author\":{\"name\":\"Amy\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d\"},\"headline\":\"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health?\",\"datePublished\":\"2025-12-16T17:22:40+00:00\",\"dateModified\":\"2025-12-16T17:22:57+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\"},\"wordCount\":645,\"publisher\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg\",\"articleSection\":[\"Blood pressure\",\"Research\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\",\"name\":\"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health? - Kidney Research UK\",\"isPartOf\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg\",\"datePublished\":\"2025-12-16T17:22:40+00:00\",\"dateModified\":\"2025-12-16T17:22:57+00:00\",\"description\":\"Dr Jess Ivy has shown that studying changes in blood vessels in the kidney could improve our understanding of heart and vessel health.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg\",\"contentUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg\",\"width\":1920,\"height\":1442,\"caption\":\"Jess Ivy, Georgios Krilis and Anastasiia Komolova in the lab\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.kidneyresearchuk.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health?\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#website\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/\",\"name\":\"Kidney Research UK\",\"description\":\"Kidney disease ends here.\",\"publisher\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.kidneyresearchuk.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#organization\",\"name\":\"Kidney Research UK\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png\",\"contentUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png\",\"width\":230,\"height\":83,\"caption\":\"Kidney Research UK\"},\"image\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/kidneyresearchuk\",\"https:\/\/x.com\/Kidney_Research\",\"https:\/\/www.instagram.com\/kidney_research_uk\/\",\"https:\/\/www.linkedin.com\/company\/kidney-research-uk\/\",\"https:\/\/www.youtube.com\/user\/KidneyResearchUK\",\"https:\/\/en.wikipedia.org\/wiki\/Kidney_Research_UK\",\"https:\/\/www.tiktok.com\/@kidney_research_uk\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d\",\"name\":\"Amy\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g\",\"caption\":\"Amy\"},\"sameAs\":[\"https:\/\/kidneyresearchuk.org\"],\"url\":\"https:\/\/www.kidneyresearchuk.org\/author\/amyyoungkidneyresearchuk-org\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health? - Kidney Research UK","description":"Dr Jess Ivy has shown that studying changes in blood vessels in the kidney could improve our understanding of heart and vessel health.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/","og_locale":"en_GB","og_type":"article","og_title":"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health? - Kidney Research UK","og_description":"Dr Jess Ivy has shown that studying changes in blood vessels in the kidney could improve our understanding of heart and vessel health.","og_url":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/","og_site_name":"Kidney Research UK","article_publisher":"https:\/\/www.facebook.com\/kidneyresearchuk","article_published_time":"2025-12-16T17:22:40+00:00","article_modified_time":"2025-12-16T17:22:57+00:00","og_image":[{"width":1920,"height":1442,"url":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg","type":"image\/jpeg"}],"author":"Amy","twitter_card":"summary_large_image","twitter_creator":"@Kidney_Research","twitter_site":"@Kidney_Research","twitter_misc":{"Written by":"Amy","Estimated reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#article","isPartOf":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/"},"author":{"name":"Amy","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d"},"headline":"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health?","datePublished":"2025-12-16T17:22:40+00:00","dateModified":"2025-12-16T17:22:57+00:00","mainEntityOfPage":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/"},"wordCount":645,"publisher":{"@id":"https:\/\/www.kidneyresearchuk.org\/#organization"},"image":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage"},"thumbnailUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg","articleSection":["Blood pressure","Research"],"inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/","url":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/","name":"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health? - Kidney Research UK","isPartOf":{"@id":"https:\/\/www.kidneyresearchuk.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage"},"image":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage"},"thumbnailUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg","datePublished":"2025-12-16T17:22:40+00:00","dateModified":"2025-12-16T17:22:57+00:00","description":"Dr Jess Ivy has shown that studying changes in blood vessels in the kidney could improve our understanding of heart and vessel health.","breadcrumb":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#primaryimage","url":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg","contentUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/Jess-Ivy_Georgios-Krilis_Anastasiia-Komolova_team-photo-in-lab.jpg","width":1920,"height":1442,"caption":"Jess Ivy, Georgios Krilis and Anastasiia Komolova in the lab"},{"@type":"BreadcrumbList","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/16\/could-understanding-blood-pressure-changes-during-sleep-in-kidney-patients-be-key-to-protecting-heart-and-vessel-health\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.kidneyresearchuk.org\/"},{"@type":"ListItem","position":2,"name":"Could understanding blood pressure changes during sleep in kidney patients be key to protecting heart and vessel health?"}]},{"@type":"WebSite","@id":"https:\/\/www.kidneyresearchuk.org\/#website","url":"https:\/\/www.kidneyresearchuk.org\/","name":"Kidney Research UK","description":"Kidney disease ends here.","publisher":{"@id":"https:\/\/www.kidneyresearchuk.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.kidneyresearchuk.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/www.kidneyresearchuk.org\/#organization","name":"Kidney Research UK","url":"https:\/\/www.kidneyresearchuk.org\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/","url":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png","contentUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png","width":230,"height":83,"caption":"Kidney Research UK"},"image":{"@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/kidneyresearchuk","https:\/\/x.com\/Kidney_Research","https:\/\/www.instagram.com\/kidney_research_uk\/","https:\/\/www.linkedin.com\/company\/kidney-research-uk\/","https:\/\/www.youtube.com\/user\/KidneyResearchUK","https:\/\/en.wikipedia.org\/wiki\/Kidney_Research_UK","https:\/\/www.tiktok.com\/@kidney_research_uk"]},{"@type":"Person","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d","name":"Amy","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g","caption":"Amy"},"sameAs":["https:\/\/kidneyresearchuk.org"],"url":"https:\/\/www.kidneyresearchuk.org\/author\/amyyoungkidneyresearchuk-org\/"}]}},"_links":{"self":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/posts\/160209","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/comments?post=160209"}],"version-history":[{"count":0,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/posts\/160209\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/media\/160210"}],"wp:attachment":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/media?parent=160209"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/categories?post=160209"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/tags?post=160209"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}