{"id":160193,"date":"2025-12-15T16:45:29","date_gmt":"2025-12-15T16:45:29","guid":{"rendered":"https:\/\/www.kidneyresearchuk.org\/?p=160193"},"modified":"2025-12-15T16:49:47","modified_gmt":"2025-12-15T16:49:47","slug":"new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure","status":"publish","type":"post","link":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/","title":{"rendered":"New blood marker can predict individuals most at risk of kidney failure"},"content":{"rendered":"\r\n

In a\u00a0study published\u00a0recently\u00a0in\u00a0Nature Communications<\/a>,\u00a0Dr Laura Denby\u00a0and collaborators\u00a0at\u00a0the\u00a0University of Edinburgh\u00a0and\u00a0Queen’s University Belfast,\u00a0with funding from Kidney Research UK, have discovered a new biomarker\u00a0in the blood\u00a0for\u00a0chronic kidney disease<\/a>\u00a0(CKD). This marker\u00a0identified\u00a0patients\u00a0at a higher risk of faster\u00a0chronic kidney disease\u00a0progression,\u00a0which\u00a0in the future\u00a0could\u00a0be used to\u00a0inform earlier\u00a0interventions to help\u00a0protect kidney health.\u00a0\u00a0<\/p>\r\n

What\u00a0are the\u00a0tests\u00a0for\u00a0kidney function?<\/h2>\r\n

CKD\u00a0is usually diagnosed<\/a>\u00a0with a\u00a0blood test, to measure the level of creatinine, and a urine test, to look at the level of protein.\u00a0Higher levels of these markers\u00a0suggest\u00a0reduced kidney function, which is\u00a0used\u00a0to\u00a0identify\u00a0the\u00a0stage\u00a0of\u00a0CKD<\/a>\u00a0and\u00a0inform\u00a0any interventions, such as\u00a0lifestyle changes,\u00a0medications,\u00a0dialysis\u00a0and transplant.\u00a0\u00a0\u00a0<\/p>\r\n

What is microRNA?<\/h2>\r\n

MicroRNAs\u00a0(miRNAs)\u00a0are small molecules that\u00a0are guardians of\u00a0whether\u00a0or not\u00a0certain proteins are made from the instructions\u00a0contained in our DNA.\u00a0They are found throughout the body, including\u00a0in\u00a0the kidneys.\u00a0<\/p>\r\n

Better\u00a0tests\u00a0are needed to\u00a0identify\u00a0patients at risk of CKD progression\u00a0<\/h2>\r\n

For\u00a0patients\u00a0with CKD,\u00a0normal\u00a0levels of\u00a0creatinine in the blood and\u00a0low\u00a0protein in the urine\u00a0can\u00a0indicate\u00a0that\u00a0their\u00a0kidneys\u00a0appear to be\u00a0working well and their\u00a0risk of disease of progression low.\u00a0However,\u00a0CKD has many\u00a0different\u00a0causes and\u00a0will affect patients differently.<\/p>\r\n

Some patients with CKD can have no or little\u00a0protein\u00a0in their urine\u00a0but still\u00a0go on to\u00a0lose\u00a0kidney function and in some cases\u00a0reach\u00a0kidney failure<\/a>.\u00a0By\u00a0identifying\u00a0these at-risk patients\u00a0early, this\u00a0new biomarker\u00a0could support the most\u00a0appropriate treatments\u00a0for their long-term kidney health.\u00a0<\/p>\r\n

Blood\u00a0microRNA\u00a0predicts CKD progression<\/h2>\r\n

Laura and the team began by looking at the genes\u00a0expressed\u00a0in blood samples\u00a0of 33 patients with\u00a0type\u00a02\u00a0diabetes<\/a>. They found a\u00a0specific type of microRNA, called\u00a0miR-190a-5p, was lower in patients\u00a0who\u00a0had\u00a0worse\u00a0kidney function.\u00a0<\/p>\r\n

By\u00a0testing\u00a0the levels of this miRNA\u00a0in a\u00a0larger group of 298 patients with CKD, they were able to\u00a0identify\u00a0lower levels\u00a0in\u00a0patients with\u00a0worse\u00a0kidney function,\u00a0this time\u00a0due to a variety of causes.\u00a0When they followed up these\u00a0patients around\u00a0four years\u00a0later, they found\u00a0that amongst\u00a0patients\u00a0who\u00a0would normally be considered at low risk of CKD progression as they\u00a0had a\u00a0low or medium level of protein in the urine,\u00a0those with\u00a0a\u00a0lower miR-190a-5p\u00a0blood\u00a0level, had an\u00a0increased risk of CKD progression,\u00a0with\u00a0some patients\u00a0reaching\u00a0kidney failure\u00a0by\u00a0this time.\u00a0<\/p>\r\n

Laura and\u00a0her collaborators\u00a0then\u00a0went on to look at\u00a0where\u00a0miR-190a-5p\u00a0is found and what role it could have in the kidney.\u00a0By examining\u00a024\u00a0biopsy samples\u00a0they\u00a0could look at how much\u00a0miR-190a-5p\u00a0was present\u00a0in the kidney. They found that\u00a0lower\u00a0levels were seen in\u00a0biopsy samples\u00a0with more\u00a0scarring\u00a0and\u00a0fewer\/smaller\u00a0tubules\u00a0(tiny tubes important\u00a0for\u00a0producing\u00a0urine\u00a0in the kidney).\u00a0Using a\u00a0laboratory\u00a0model they\u00a0found\u00a0restoring the\u00a0levels of\u00a0miR-190a-5p\u00a0in kidney injury\u00a0both\u00a0reduced scarring\u00a0and improved kidney health.\u00a0\u00a0<\/p>\r\n

What could this mean for patients?<\/h2>\r\n

This\u00a0new blood\u00a0marker\u00a0could in\u00a0the\u00a0future help healthcare providers\u00a0to\u00a0identify\u00a0patients with\u00a0a high likelihood of CKD progression,\u00a0who\u00a0may not\u00a0be\u00a0identified\u00a0using current kidney function tests.\u00a0<\/p>\r\n

This\u00a0could\u00a0mean\u00a0more regular monitoring, and\u00a0earlier interventions\u00a0for these patients,\u00a0such as\u00a0medications to\u00a0try and\u00a0protect kidney health and\u00a0slow\u00a0the progression of CKD.\u00a0<\/p>\r\n

In the longer term, therapies\u00a0could be developed\u00a0to restore the level of miR-190-5p in the kidneys of patients with CKD\u00a0which\u00a0may reduce renal scarring and preserve kidney function.\u00a0<\/p>\r\n

\"Black

“This research\u00a0has been supported by Kidney Research UK throughout\u00a0its\u00a0journey,\u00a0from discovery of this\u00a0microRNA molecule in the lab,\u00a0to\u00a0translating this into patients.<\/p>\r\n

“My interest in miRNAs goes back to my post-doctoral fellowship, and the CKD patient samples used in this study came from seNSOR, both of these projects as well as my senior fellowship were funded by Kidney Research UK.<\/p>\r\n

“We’re now at the stage where these results could inform better testing for CKD and improve things for patients which is why I do the research I’m doing.<\/p>\r\n

“I am very grateful to Kidney Research UK’s supporters for making this possible.” Dr Laura Denby\u00a0<\/b>\u00a0<\/p>\r\n

 <\/p>\r\n

\"Kidney

Have you been diagnosed with kidney disease?<\/h2>\r\n

Request your free Kidney Kit today.<\/p>\r\n

You’ll find tips and support from kidney patients, delicious recipes, simple exercise plans and more.<\/p>\r\n

Get your free Kidney Kit <\/a><\/p>\r\n

Why not make a donation now?<\/h2>\r\n

Every \u00a3 counts towards transforming treatments for people living with kidney disease.<\/p>\r\n

Donate now <\/a><\/p>\r\n","protected":false},"excerpt":{"rendered":"

In a\u00a0study published\u00a0recently\u00a0in\u00a0Nature Communications,\u00a0Dr Laura Denby\u00a0and collaborators\u00a0at\u00a0the\u00a0University of Edinburgh\u00a0and\u00a0Queen’s University Belfast,\u00a0with funding from Kidney Research UK, have discovered a new biomarker\u00a0in the blood\u00a0for\u00a0chronic kidney disease\u00a0(CKD). This marker\u00a0identified\u00a0patients\u00a0at a higher risk of faster\u00a0chronic kidney disease\u00a0progression,\u00a0which\u00a0in the future\u00a0could\u00a0be used to\u00a0inform earlier\u00a0interventions to help\u00a0protect kidney health.\u00a0\u00a0 What\u00a0are the\u00a0tests\u00a0for\u00a0kidney function? CKD\u00a0is usually diagnosed\u00a0with a\u00a0blood test, to measure the level…<\/p>\n","protected":false},"author":3,"featured_media":160194,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_searchwp_excluded":"","footnotes":""},"categories":[1],"tags":[],"class_list":["post-160193","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorised"],"acf":[],"yoast_head":"\nNew blood marker can predict individuals most at risk of kidney failure - Kidney Research UK<\/title>\n<meta name=\"description\" content=\"Dr Laura Denby at the University of Edinburgh has discovered a new biomarker in the blood for chronic kidney disease (CKD).\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New blood marker can predict individuals most at risk of kidney failure - Kidney Research UK\" \/>\n<meta property=\"og:description\" content=\"Dr Laura Denby at the University of Edinburgh has discovered a new biomarker in the blood for chronic kidney disease (CKD).\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\" \/>\n<meta property=\"og:site_name\" content=\"Kidney Research UK\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/kidneyresearchuk\" \/>\n<meta property=\"article:published_time\" content=\"2025-12-15T16:45:29+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-12-15T16:49:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"2560\" \/>\n\t<meta property=\"og:image:height\" content=\"1707\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Amy\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Kidney_Research\" \/>\n<meta name=\"twitter:site\" content=\"@Kidney_Research\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Amy\" \/>\n\t<meta name=\"twitter:label2\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\"},\"author\":{\"name\":\"Amy\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d\"},\"headline\":\"New blood marker can predict individuals most at risk of kidney failure\",\"datePublished\":\"2025-12-15T16:45:29+00:00\",\"dateModified\":\"2025-12-15T16:49:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\"},\"wordCount\":788,\"publisher\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg\",\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\",\"name\":\"New blood marker can predict individuals most at risk of kidney failure - Kidney Research UK\",\"isPartOf\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg\",\"datePublished\":\"2025-12-15T16:45:29+00:00\",\"dateModified\":\"2025-12-15T16:49:47+00:00\",\"description\":\"Dr Laura Denby at the University of Edinburgh has discovered a new biomarker in the blood for chronic kidney disease (CKD).\",\"breadcrumb\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg\",\"contentUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg\",\"width\":2560,\"height\":1707,\"caption\":\"Vacutainer tubes with blood.\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.kidneyresearchuk.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"New blood marker can predict individuals most at risk of kidney failure\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#website\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/\",\"name\":\"Kidney Research UK\",\"description\":\"Kidney disease ends here.\",\"publisher\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.kidneyresearchuk.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#organization\",\"name\":\"Kidney Research UK\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png\",\"contentUrl\":\"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png\",\"width\":230,\"height\":83,\"caption\":\"Kidney Research UK\"},\"image\":{\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/kidneyresearchuk\",\"https:\/\/x.com\/Kidney_Research\",\"https:\/\/www.instagram.com\/kidney_research_uk\/\",\"https:\/\/www.linkedin.com\/company\/kidney-research-uk\/\",\"https:\/\/www.youtube.com\/user\/KidneyResearchUK\",\"https:\/\/en.wikipedia.org\/wiki\/Kidney_Research_UK\",\"https:\/\/www.tiktok.com\/@kidney_research_uk\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d\",\"name\":\"Amy\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g\",\"caption\":\"Amy\"},\"sameAs\":[\"https:\/\/kidneyresearchuk.org\"],\"url\":\"https:\/\/www.kidneyresearchuk.org\/author\/amyyoungkidneyresearchuk-org\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New blood marker can predict individuals most at risk of kidney failure - Kidney Research UK","description":"Dr Laura Denby at the University of Edinburgh has discovered a new biomarker in the blood for chronic kidney disease (CKD).","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/","og_locale":"en_GB","og_type":"article","og_title":"New blood marker can predict individuals most at risk of kidney failure - Kidney Research UK","og_description":"Dr Laura Denby at the University of Edinburgh has discovered a new biomarker in the blood for chronic kidney disease (CKD).","og_url":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/","og_site_name":"Kidney Research UK","article_publisher":"https:\/\/www.facebook.com\/kidneyresearchuk","article_published_time":"2025-12-15T16:45:29+00:00","article_modified_time":"2025-12-15T16:49:47+00:00","og_image":[{"width":2560,"height":1707,"url":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg","type":"image\/jpeg"}],"author":"Amy","twitter_card":"summary_large_image","twitter_creator":"@Kidney_Research","twitter_site":"@Kidney_Research","twitter_misc":{"Written by":"Amy","Estimated reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#article","isPartOf":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/"},"author":{"name":"Amy","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d"},"headline":"New blood marker can predict individuals most at risk of kidney failure","datePublished":"2025-12-15T16:45:29+00:00","dateModified":"2025-12-15T16:49:47+00:00","mainEntityOfPage":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/"},"wordCount":788,"publisher":{"@id":"https:\/\/www.kidneyresearchuk.org\/#organization"},"image":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage"},"thumbnailUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg","inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/","url":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/","name":"New blood marker can predict individuals most at risk of kidney failure - Kidney Research UK","isPartOf":{"@id":"https:\/\/www.kidneyresearchuk.org\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage"},"image":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage"},"thumbnailUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg","datePublished":"2025-12-15T16:45:29+00:00","dateModified":"2025-12-15T16:49:47+00:00","description":"Dr Laura Denby at the University of Edinburgh has discovered a new biomarker in the blood for chronic kidney disease (CKD).","breadcrumb":{"@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#primaryimage","url":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg","contentUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2025\/12\/testalize-me-0jE8ynV4mis-unsplash-scaled.jpg","width":2560,"height":1707,"caption":"Vacutainer tubes with blood."},{"@type":"BreadcrumbList","@id":"https:\/\/www.kidneyresearchuk.org\/2025\/12\/15\/new-blood-marker-can-predict-individuals-most-at-risk-of-kidney-failure\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.kidneyresearchuk.org\/"},{"@type":"ListItem","position":2,"name":"New blood marker can predict individuals most at risk of kidney failure"}]},{"@type":"WebSite","@id":"https:\/\/www.kidneyresearchuk.org\/#website","url":"https:\/\/www.kidneyresearchuk.org\/","name":"Kidney Research UK","description":"Kidney disease ends here.","publisher":{"@id":"https:\/\/www.kidneyresearchuk.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.kidneyresearchuk.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/www.kidneyresearchuk.org\/#organization","name":"Kidney Research UK","url":"https:\/\/www.kidneyresearchuk.org\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/","url":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png","contentUrl":"https:\/\/www.kidneyresearchuk.org\/wp-content\/uploads\/2019\/07\/kruk-logo_small.png","width":230,"height":83,"caption":"Kidney Research UK"},"image":{"@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/kidneyresearchuk","https:\/\/x.com\/Kidney_Research","https:\/\/www.instagram.com\/kidney_research_uk\/","https:\/\/www.linkedin.com\/company\/kidney-research-uk\/","https:\/\/www.youtube.com\/user\/KidneyResearchUK","https:\/\/en.wikipedia.org\/wiki\/Kidney_Research_UK","https:\/\/www.tiktok.com\/@kidney_research_uk"]},{"@type":"Person","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/944c0555317b7ac0c28c50a939837d1d","name":"Amy","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/www.kidneyresearchuk.org\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/784acb01fb35976fa11f7d20655c868cb52ad1e2afab28fe4213d85dcd7a8ad0?s=96&d=mm&r=g","caption":"Amy"},"sameAs":["https:\/\/kidneyresearchuk.org"],"url":"https:\/\/www.kidneyresearchuk.org\/author\/amyyoungkidneyresearchuk-org\/"}]}},"_links":{"self":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/posts\/160193","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/comments?post=160193"}],"version-history":[{"count":0,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/posts\/160193\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/media\/160194"}],"wp:attachment":[{"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/media?parent=160193"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/categories?post=160193"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.kidneyresearchuk.org\/wp-json\/wp\/v2\/tags?post=160193"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}